Focus Factor vs. Prevagen: Going Broad or Going Deep

Last Updated on May 12, 2021 by James Matthews

“Nootropics” is a fancy new buzzword floating around health and wellness circles. The term stems from the Greek word nous meaning “mind” or “intellect.” The promise of nootropics is that they can improve your cognitive functioning and make you more effective at using your brain.

Two popular brain-boosting supplements on the market are Focus Factor and Prevagan. Both supplements have gotten fairly popular recently and both claim to improve your memory and concentration. But both supplements have different ingredients. Prevagen relies on a special ingredient while Focus Factor contains a more general blend of vitamins and minerals.

So the question arises: Which supplement, Focus Factor vs. Prevagen, is better? We will talk about both Focus Factor and Prevagen, compare their ingredients and effects, and talk about their benefits and disadvantages. We will then give our verdict on which memory supplement we think is better

What Are Nootropics?

Basically, a nootropic is a substance that increases cognitive ability and performance. Keep in mind that the term “nootropic” is more of a marketing buzzword rather than an actual medical term. That means that the same companies will use the term “nootropic” to describe the products that otherwise do not share much in common.

So what actually matters is the ingredients that the nootropic uses. Caffeine could be a nootropic because caffeine improves mental focus and reflex time. But most people are expecting something a little bit more unorthodox than simple caffeine when they hear the fancy term “nootropic.”

So when researching nootropics, what you should focus on is the actual ingredients. Don’t let a term like “nootropic” confuse you; it’s mostly just marketing fluff. Instead look at the product label, research the individual ingredients, and see what kind of evidence there is for their effectiveness.

Focus Factor

Focus Factor vs Prevagen

This is a company that produces a wide range of nootropic supplements designed to improve concentration and mental focus. Focus Factor stands apart from other nootropic supplements as it claims it has clinical evidence behind the efficacy of its blends. Focus Factor has a huge range of vitamins and may more properly be called a multivitamin rather than a nootropic.


Focus Factor vs Prevagen


This is a compound that works in the brain to facilitate neural generation and neural communication. Choline is actually a very important nutrient because the body cannot synthesize it on its own, and so get it from external sources.

B Vitamins

B vitamins do all kinds of things in the body, B vitamins help directly facilitate cellular metabolism, which gives you more energy. More energy means more focus, so B vitamins are a common addition in nootropics and other energy-boosting supplements.

Gamma-aminobutyric acid (GABA)

GABA is a very important neurotransmitter that regulates neural activity by dampening neuron response. GABA is very important for all kinds of things like improving mood, relieving anxiety, and promoting fat burn and muscle growth.


Tyrosine is an amino acid that serves as a precursor to phenylalanine, another amino acid. These two compounds are necessary for the formation of dopamine, norepinephrine, and epinephrine. They improve attention, focus, and memory. Tyrosine is also a common ingredient in several energy drinks.


Vinpocetine is a chemical that improves memory and enhances brain metabolism. It is used in Germany as a prescription drug in several forms. However, it is not common in the US. Vinpocetine also promotes brain healing after ischemic attacks and strokes. Some argue the clinical efficacy of Vinpocetine is debatable.


Bacopin is derived from the Bacopa plant. It has been used for centuries in Indian medicine to treat memory and other cognitive conditions. There is some evidence that Bacopin can improve the production of dopamine, noradrenaline, and serotonin. However, there is still debate over the clinical efficacy of Bacopa in the west.

Additional Ingredients

In addition to all of these special ingredients in the proprietary blend, Focus Factor has pretty much every regular vitamin you need including vitamin D, potassium, chromium, folate, molybdenum, riboflavin, selenium, thiamin, calcium, niacin, copper, magnesium, zinc, manganese, and more. The inclusion of all these ingredients makes us inclined to label Focus Factor Original more of a multivitamin rather than a dedicated nootropic.

Focus Factor Side Effects

Focus Factor contains over 40 distinct ingredients so, as you might expect, there are some potential side effects.

A common side effect of choline is gastrointestinal distress and bloating. Diarrhea and vomiting might also be symptoms of too much choline. Some ingredients in Focus Factor such as l-glutamine are linked to muscle pain and headaches, as well as dry mouth and rash.

Bilberry affects blood sugar levels, so those with diabetes should not take this product. Grapefruit extract can cause itchiness and dizziness in high doses.

The main problem is that most of the ingredients that have side effects are contained in the proprietary blend, so we don’t know the actual proportions and amounts of these ingredients. Common side effects reported by users include stomach pain, headaches, irritability, and upset stomach. A handful of consumers also report insomnia and fishy body odor.

Focus Factor Pros

  • Contains a wide range of common vitamins with proven benefits
  • Many ingredients in the proprietary blend have some evidence suggesting they are effective for improving cognitive performance
  • It has several varieties of their original blend, including one for brain & vision and another line tailored for children.
  • The nootropic is reasonably priced and will not put a huge hole in your wallet
  • It comes in convenient capsule form and is easy to take

Focus Factor Cons

  • Several of the ingredients in the proprietary blend have side effects, including diarrhea, upset stomach, dry mouth, and more.
  • There is still a lot of debate about the effectiveness of various ingredients that the supplement includes
  • A large amount of ingredients means that it might interact with other substances or meditations in unexpected ways.


Focus Factor vs Prevagen

This is a relatively new nootropic supplement that is popular for its use against memory loss. The supplement also claims that it can boost mood and delay the onset of certain neurodegenerative conditions like Alzheimer’s or Parkinson’s’. Prevagen is created by Quincy Bioscience, a biotech company based out of Wisconsin.


Focus Factor vs Prevagen

Compared to Focus Factor, Prevagen is very scant on ingredients. Focus Factor has over 40 ingredients but Prevagen only has 2 active ingredients, vitamin D and apoaequorin.

Vitamin D

Vitamin D is a well-known mineral and has been found to have a significant effect on memory and other mental tests. Those who are deficient in vitamin D are much more likely to perform negatively on cognitive assessments than those who are not deficient in vitamin D.


The other major ingredient is apoaequorin. This is special protein derived from jellyfish. There is some clinical evidence that apoaequorin might help with neurodegeneration in the brain and improve cognitive functioning. Apoaequorin interacts with calcium. Problems with calcium in the brain play a role in age-related mental decline, and apoaequorin helps with this. Apoaequorin allegedly supports healthy brain functioning as you age.

There are a decent amount of studies indicating that apoaequorin is safe to ingest and is nontoxic in small to mild doses. There is also some evidence that apoaequorin might help improve sleep.

FTC Investigation

We should mention that Prevagen has been in some hot water in the past. The Federal Trade Commission (FTC) has charged Quincy Bioscience, the creator of Prevagen, with false and deceptive advertising, particularly about the apoaequorin ingredient.

The charge against Quincy Bioscience never stuck as a judge dismissed the case, but the company does not appear to have run any further tests on their supplement. Alternatively, other studies have indicated that apoaequorin might have some memory benefits, but only in older adults and only a very small difference. More research is necessary to determine its actual effectiveness.

Prevagen Side Effects

For the most part, small to moderate doses of apoaequorin is perfectly safe for adult humans to take and are not associated with any serious side effects. However, there is not much evidence about potential side effects at higher concentrations. Common side effects include headache, dizziness, and nausea, most of which are mild and subsist eventually.

In a handful of cases, apoaequorin consumption has been associated with heart and nervous system problems, but in these cases, it is unclear whether apoaequorin was the cause in those cases or just incidental. There is also little evidence on how Prevagen interacts with other medications.

Prevagen Pros

  • Only two ingredients. If the large amount of ingredients in Focus Factor worries you then you might feel more comfortable taking Prevagen
  • The main ingredient in Prevagen, apoaequorin, has some beneficial effects on memory in older adults. However, it is not sure whether Prevagen itself is effective for memory.
  • Prevagen and apoaequorin are nontoxic and safe to consume for human adults
  • Prevagen is relatively affordable and won’t break the bank when buying

Prevagen Cons

  • Prevagen might also contain mils, nuts, and soy, all three of which are common allergens.
  • The actual effectiveness of apoaequorin is still up for debate and more research is necessary.
  • The FTc charged the creator of Prevagen for false advertising.

So, which is better: Focus Factor vs. Prevagen?

In our estimation, we would say that Focus Factor is the better option to choose from. Focus Factor might be more of a generic multivitamin than a fancy nootropic, but it has a lot of decent vitamins and minerals, along with a proprietary blend that has a lot of ingredients with some demonstrated positive effects.

Even if Focus Factor does not help your memory and cognitive functioning very much, then it still has some good ingredients in it such as vitamin B, riboflavin, manganese, iron, and so on. These are all useful things that can help your mental concentration by making sure you are not deficient in any nutrients. But it might be a stretch to say that Focus Factor is a real “nootropic” rather than a regular multivitamin with some unique ingredients and a fancy name.

The problem with Prevagen is that it puts its entire operation on a single ingredient that has mixed data about its effects. So, if you are currently trying to decide between Focus Factor and Prevagen then we would recommend going with Focus Factor.

At the end of the day, nootropics are a tough category to nail down, so make sure that when buying that you are researching the individual ingredients rather than relying on marketing terms like “nootropics.”